Yasuhiko Kizuka Selected Research

alpha-1,6-mannosylglycoprotein beta 1,6-N-acetylglucosaminyltransferase

4/2022	Cryostorage of unstable N-acetylglucosaminyltransferase-V by synthetic zwitterions.
1/2022	Structure-based design of UDP-GlcNAc analogs as candidate GnT-V inhibitors.
1/2022	N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates.
12/2020	Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V.
1/2018	Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.

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Yasuhiko Kizuka Research Topics

Disease

18	Neoplasms (Cancer) 04/2022 - 01/2015
8	Alzheimer Disease (Alzheimer's Disease) 08/2021 - 02/2015
4	Emphysema 11/2018 - 04/2014
4	Chronic Obstructive Pulmonary Disease (COPD) 11/2018 - 09/2015
3	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 01/2016
2	Melanoma (Melanoma, Malignant) 01/2019 - 01/2019
2	Inflammation (Inflammations) 12/2017 - 01/2017
2	Demyelinating Diseases (Demyelinating Disease) 01/2017 - 06/2013
1	Autoimmune Diseases (Autoimmune Disease) 01/2022
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2022
1	Pathologic Processes 01/2021
1	Thrombosis (Thrombus) 01/2021
1	Experimental Melanoma 01/2019
1	Pneumonia (Pneumonitis) 11/2018
1	Hepatocellular Carcinoma (Hepatoma) 12/2017
1	Pulmonary Emphysema 11/2017
1	Obesity 10/2017
1	Nervous System Diseases (Neurological Disorders) 11/2016
1	Parkinson Disease (Parkinson's Disease) 04/2016
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 04/2016
1	Oligodendroglioma 10/2014
1	Disease Progression 04/2014

Drug/Important Bio-Agent (IBA)

20	Polysaccharides (Glycans)IBA 01/2022 - 06/2013
11	EnzymesIBA 04/2022 - 01/2015
9	Proteins (Proteins, Gene)FDA Link 04/2022 - 02/2015
7	FucoseIBA 12/2017 - 04/2014
5	alpha-1,6-mannosylglycoprotein beta 1,6-N-acetylglucosaminyltransferaseIBA 04/2022 - 01/2018
5	Pharmaceutical PreparationsIBA 01/2022 - 02/2015
5	SugarsIBA 01/2021 - 01/2015
4	GlycosyltransferasesIBA 01/2021 - 04/2014
3	NucleotidesIBA 01/2021 - 01/2015
3	Amyloid (Amyloid Fibrils)IBA 01/2016 - 02/2015
2	Biological ProductsIBA 01/2021 - 01/2015
2	Glycoproteins (Glycoprotein)IBA 01/2021 - 09/2015
2	FucosyltransferasesIBA 01/2021 - 11/2017
2	DisaccharidesIBA 11/2018 - 01/2017
2	Keratan SulfateIBA 11/2018 - 01/2017
2	CuprizoneIBA 01/2017 - 06/2013
2	SmokeIBA 01/2017 - 09/2015
2	Biomarkers (Surrogate Marker)IBA 04/2016 - 09/2015
2	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 02/2015
2	LectinsIBA 09/2015 - 01/2015
1	Biocompatible Materials (Biomaterials)IBA 04/2022
1	AcetylgalactosamineIBA 01/2022
1	UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferaseIBA 01/2022
1	PrionsIBA 01/2022
1	TransferasesIBA 01/2021
1	GlycolipidsIBA 01/2021
1	Glycoside Hydrolases (Endoglycosidases)IBA 01/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021
1	Proteoglycans (Proteoglycan)IBA 01/2021
1	N-AcetylglucosaminyltransferasesIBA 01/2021
1	AcetylglucosamineIBA 12/2020
1	dolichyl-diphosphooligosaccharide - protein glycotransferase (oligosaccharyltransferase)IBA 12/2019
1	Sucrose (Saccharose)IBA 01/2019
1	AsparagineIBA 01/2019
1	Detergents (Detergent)IBA 01/2019
1	C-Type Lectins (C-Type Lectin)IBA 11/2018
1	GlycosaminoglycansIBA 11/2018
1	IntegrinsIBA 01/2018
1	Angiogenesis InhibitorsIBA 01/2018
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2018
1	Cell Surface ReceptorsIBA 01/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018
1	Guanosine Diphosphate Fucose (GDP Fucose)IBA 12/2017
1	Toll-Like Receptor 4IBA 11/2017
1	Mannose (D-Mannose)IBA 01/2017
1	Pancreatic Elastase (Elastase)IBA 01/2017
1	CytokinesIBA 01/2017
1	AntibodiesIBA 01/2017
1	Matrix Metalloproteinases (MMPs)IBA 01/2017
1	Peroxidase (Myeloperoxidase)IBA 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2016
1	Reactive Nitrogen SpeciesIBA 04/2016
1	GlycoconjugatesIBA 01/2016
1	AntioxidantsIBA 01/2016
1	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 09/2015
1	Peptides (Polypeptides)IBA 02/2015
1	alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferaseIBA 01/2015
1	Tumor Biomarkers (Tumor Markers)IBA 01/2015
1	LuciferasesIBA 10/2014
1	Transcription Factors (Transcription Factor)IBA 10/2014

Therapy/Procedure

2	Therapeutics 04/2016 - 01/2015